The P-Shot® – Using PRP for Erectile Dysfunction
Dr. Charles Runels, inventor of the Vampire Facelift® and the O-Shot®, developed the Priapus Shot® (P-Shot®) to use platelet-rich plasma (PRP) as a treatment option for erectile dysfunction. As men age, reduced circulation and hormonal changes can affect the ability to achieve and maintain firm erections, leading many to search for solutions beyond medication alone.
At Smooth Solutions Medical Aesthetics in Williamsville, New York, Jack Bertolino, MD, is a board-certified family physician with fellowship training in geriatrics and functional medicine. He offers the P-Shot® as part of his focus on regenerative and pro-aging care for men. With years of experience in PRP therapies and hormone health, Dr. Bertolino provides an evidence-based, in-office approach to support improved blood flow, sensitivity, and sexual performance.
P-Shot® Radio Spot
What is the P-Shot?
The Priapus Shot uses a patient’s own blood platelets and stem cells to improve penile function.
Utilizing the healing and regeneration power of platelets, the P-Shot stimulates new tissue growth and increases blood flow. The P-Shot procedure is a fast, painless injection intended for men who have lost function due to an enlarged prostate, prostate cancer, drug side effects, conditions such as diabetes, or the after-effects from surgery.
Named for Priapus, the Greek god of virility, the P-Shot can be an effective treatment for erectile dysfunction.
Patient Testimonial
"Dr. Bertolino has been treating me for about two years. He takes the time to listen to your concerns and has reasonable solutions. You never get the feeling that he is trying to sell you something He actually cares that the services he provides is helping you. And it has helped me. I appreciate his approach and his solutions."
How the P-Shot® helps with ED
The growth factors present in platelet-rich plasma stimulate the growth of new tissue and blood vessels in the penis, increasing the size and blood flow.
The goal of the Priapus Shot® injection is to use PRP to enhance the patient’s erections, enlarge the penis, and create greater sensitivity and thus satisfaction.
How can a patient with ED benefit from the P-Shot®?
The P-Shot® is ideal for enhancing the penis and providing a more pleasurable sex life for aging men. The advantages of the P-Shot® include:
- Although it will decrease slightly 3-5 days following the initial injections, men will experience a larger penis within 4-6 weeks
- Firmer and stronger erections
- Straightening of the penis
- Increased circulation and blood flow in the penis
- Increased sensation
- Enhances the effects of other therapies such as Viagra
- No allergic reactions
How the P-Shot® procedure is performed
To begin with, lidocaine cream is applied topically to the patient’s penis. Similarly to the O-Shot®, a small vial of blood is then drawn, and the PRP is separated before a few drops of calcium chloride are added to activate the growth factors.
Next, a tiny needle is used to inject the PRP back into the penis. The injection locations are the corpus cavernosum and the head of the penis. These injection sites and the protocols used are patent-protected and performed by physicians trained specifically in PRP treatments.
Who Is a Good Candidate for the P-Shot®?
A good candidate for the P-Shot® is a man experiencing mild to moderate erectile dysfunction who wants to improve firmness, sensitivity, or overall sexual performance without relying solely on medication. It may also benefit men who have noticed changes after prostate surgery, diabetes, hormonal shifts, or age-related circulation decline.
Because the treatment uses your own platelet-rich plasma, most healthy men are eligible, but a consultation is important to determine whether this approach fits your medical history and goals.
When will I see my results after I receive the P-Shot?
Improvements in erection quality and duration will be seen 4-6 weeks after treatment. Noticeable increases in size will take a few weeks to allow for tissue regeneration and other growth factors to take effect. Results are variable between patients.
When Can I Resume Sexual Activity After Treatment?
Most men can resume sexual activity within 24 hours after the procedure. There is little to no downtime, though mild swelling or tenderness at the injection site may occur briefly. Dr. Bertolino will provide specific guidance based on your individual response, but in general, normal activity can return quickly.
Why Choose Dr. Bertolino for the P-Shot®?
Dr. Jack G. Bertolino, MD, earned his medical degree from New York Medical College and completed residency training in both general surgery and family medicine, followed by a fellowship in geriatrics at SUNY Buffalo. He also completed a fellowship in Functional Medicine through the American Academy of Anti-Aging and Regenerative Medicine (A4M). His background allows him to evaluate sexual health concerns through a broader lens, including circulation, hormone balance, and overall wellness.
Dr. Bertolino has provided advanced aesthetic and regenerative treatments since 2006. He has extensive experience with PRP therapies and bioidentical hormone replacement for men, making him well-versed in the science behind the P-Shot®. Patients value his thorough consultations and focus on individualized care designed to support long-term sexual health and performance.
Patient Testimonial
"I had prostate cancer and had my prostate removed when I was 42 years old. I am now 55. During that period I went through different events in my life, including divorce. As a result, for the first time in a long time, I was facing the prospect of dating again and being sexually active. Exciting yes, but scary at the same time. This is the case for anyone, but when you have had your prostate removed, you can feel less than sure.
I started looking for different options and treatments. There are pills, but still wanted something more, something to give me more confidence. This is when I came upon Dr. Bertolino and the P Shot. He spent a lot of time with me and we discussed my condition in detail. He never pushed the treatment and told me to go home, read some more and then let him know. I decided to move ahead. The procedure was painless and did not take long. Dr. Bertolino was great explaining everything that was happening and made me feel comfortable.
As to the results, the P Shot, for me, it did allow me to have erections, not all of the time, without pills, and the shot gave me bigger size and girth. That may not sound like much, but when you have had your prostate removed, it is a big deal.
At the end of the day, it is about confidence, about giving yourself the opportunity. The P Shot gave me that opportunity and Dr. Bertolino was the one who provided it with honesty, integrity and a genuine caring for me.
I definitely recommend going in to see Dr. Bertolino. At the end of the day, everyone is different, but again, it is about giving yourself the opportunity."
Frequently Asked Questions
Improvements in erection quality and duration will be seen 4-6 weeks after treatment. Noticeable increases in size will take a few weeks to allow for tissue regeneration and other growth factors to take effect. Results are variable between patients.
The P-Shot improves symptoms of erectile dysfunction in men for one year. These results can vary between patients, but generally, patients experience stronger, longer, and firmer erections.
There is no pain involved in this treatment. Prior to the procedure, the injection area is fully numbed with topical lidocaine. Dr. Bertolino uses a very fine, short needle for these injections, as well.
No. These are considered to be elective procedures, so they are not covered by health insurance.
Some men find they no longer need medication after treatment, while others notice they require a lower dose for better results. The response varies depending on the severity of erectile dysfunction and overall health. The P-Shot® may improve blood flow and tissue health, which can enhance natural erections and, in some cases, improve how medications work if they are still used.
Yes. The P-Shot® can be combined with bioidentical hormone replacement therapy when low testosterone or other hormonal imbalances contribute to erectile dysfunction. Addressing both circulation and hormone levels often provides a more comprehensive approach to improving sexual performance and vitality.
Many men begin with one treatment and evaluate their results over the following weeks. Depending on the degree of dysfunction and desired improvement, some patients may benefit from a second treatment several months later. Dr. Bertolino will discuss a plan tailored to your needs.
Because the P-Shot® uses your own platelet-rich plasma, the risk of allergic reaction is extremely low. Mild swelling, redness, or temporary sensitivity at the injection site can occur but typically resolves quickly. As with any injection-based procedure, there is a small risk of bruising or minor discomfort, which is generally short-lived.
What are the alternatives to the P-Shot?
Some degree of erectile dysfunction will impact virtually all men as they pass their 50th or 55th birthday. It’s a simple fact of life that the male circulatory system doesn’t deliver the amount of blood to the penis as it did in the patient’s younger days. Blood vessels can also constrict as another widespread part of aging.
The alternative to the P-Shot is the use of drugs to treat erectile dysfunction. You know the brand names of these drugs. Most of them have now lost their patent exclusivity and are available by their generic names as well.
These are the available drugs:
- Sildenafil (Viagra)
- Tadalafil (Adcirca, Cialis)
- Vardenafil (Levitra, Staxyn)
- Avanafil (Stendra)
Many men prefer the P-Shot because it uses their own blood platelets to improve circulation, rather than prescription drugs.
Another alternative treatment is acoustic wave therapy, which uses the energy from low-intensity shock waves to trigger a process called neovascularization in the penis, creating new blood vessels and a new blood supply in the corpus cavernosum of the penile shaft, which improves and increases blood flow.
Schedule a Consultation
If you are looking for an alternative to ED medications and are interested in the P-Shot® in Buffalo or Williamsville, NY, contact us today to schedule an appointment! Call 716-633-6100 or fill out our contact form today.
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